BRCAmut and “founder effect”: a prospective study in a single academic institution

INTRODUCTION: About 25% of ovarian cancers can be classified as hereditary. Of these, 80–90% are correleted with the Hereditary Breast–Ovarian Cancer Syndrome (HBOC), which is linked to BRCA 1/2 genes mutations. Our study was set up to study the BRCA-mutation incidence in Apulian population affected...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Loizzi, Vera, Cicinelli, Ettore, Santamaria, Francesco, Murgia, Ferdinando, Minicucci, Valentina, Resta, Leonardo, Resta, Nicoletta, Natalicchio, Maria Iole, Ranieri, Girolamo, Cormio, Gennaro
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2018
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5976469/
https://ncbi.nlm.nih.gov/pubmed/29854283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24959
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