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AmpliSeq transcriptome analysis of human alveolar and monocyte-derived macrophages over time in response to Mycobacterium tuberculosis infection

Human alveolar macrophages (HAM) are primary bacterial niche and immune response cells during Mycobacterium tuberculosis (M.tb) infection, and human blood monocyte-derived macrophages (MDM) are a model for investigating M.tb-macrophage interactions. Here, we use a targeted RNA-Seq method to measure...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Papp, Audrey C., Azad, Abul K., Pietrzak, Maciej, Williams, Amanda, Handelman, Samuel K., Igo, Robert P., Stein, Catherine M., Hartmann, Katherine, Schlesinger, Larry S., Sadee, Wolfgang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5976201/
https://ncbi.nlm.nih.gov/pubmed/29847580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0198221
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