Post-trial follow-up methodology in large randomised controlled trials: a systematic review

BACKGROUND: Randomised controlled clinical trials typically have a relatively brief in-trial follow-up period which can underestimate safety signals and fail to detect long-term hazards, which may take years to appear. Extended follow-up after the scheduled closure of the trial allows detection of b...

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Dettagli Bibliografici
Pubblicato in:Trials
Autori principali: Llewellyn-Bennett, Rebecca, Edwards, Danielle, Roberts, Nia, Hainsworth, Atticus H., Bulbulia, Richard, Bowman, Louise
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
Soggetti:
Review
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5975470/
https://ncbi.nlm.nih.gov/pubmed/29843774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-018-2653-0
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