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Regulatory Network of ARF in Cancer Development

ARF is a tumor suppressor protein that has a pivotal role in the prevention of cancer development through regulating cell proliferation, senescence, and apoptosis. As a factor that induces senescence, the role of ARF as a tumor suppressor is closely linked to the p53-MDM2 axis, which is a key proces...

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Detalhes bibliográficos
Publicado no:Mol Cells
Main Authors: Ko, Aram, Han, Su Yeon, Song, Jaewhan
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Society for Molecular and Cellular Biology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5974615/
https://ncbi.nlm.nih.gov/pubmed/29665672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14348/molcells.2018.0100
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