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Host Factor SPCS1 Regulates the Replication of Japanese Encephalitis Virus through Interactions with Transmembrane Domains of NS2B

Signal peptidase complex subunit 1 (SPCS1) is a newly identified host factor that regulates flavivirus replication, but the molecular mechanism is not fully understood. Here, using Japanese encephalitis virus (JEV) as a model, we investigated the mechanism through which the host factor SPCS1 regulat...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Ma, Le, Li, Fang, Zhang, Jing-Wei, Li, Wei, Zhao, Dong-Ming, Wang, Han, Hua, Rong-Hong, Bu, Zhi-Gao
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5974503/
https://ncbi.nlm.nih.gov/pubmed/29593046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00197-18
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