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Human metapneumovirus inhibits the IL-6-induced JAK/STAT3 signalling cascade in airway epithelium

The host cytokine IL-6 plays an important role in host defence and prevention of lung injury from various pathogens, making IL-6 an important mediator in the host’s susceptibility to respiratory infections. The cellular response to IL-6 is mediated through a Janus kinase/signal transducer and activa...

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Detalhes bibliográficos
Publicado no:J Gen Virol
Main Authors: Mitzel, Dana N., Jaramillo, Richard J., Stout-Delgado, Heather, Senft, Albert P., Harrod, Kevin S.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for General Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5974310/
https://ncbi.nlm.nih.gov/pubmed/24114793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.055632-0
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