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Rational Design and Evaluation of an Artificial Escherichia coli K1 Protein Vaccine Candidate Based on the Structure of OmpA

Escherichia coli (E. coli) K1 causes meningitis and remains an unsolved problem in neonates, despite the application of antibiotics and supportive care. The cross-reactivity of bacterial capsular polysaccharides with human antigens hinders their application as vaccine candidates. Thus, protein antig...

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Detalhes bibliográficos
Publicado no:Front Cell Infect Microbiol
Main Authors: Gu, Hao, Liao, Yaling, Zhang, Jin, Wang, Ying, Liu, Zhiyong, Cheng, Ping, Wang, Xingyong, Zou, Quanming, Gu, Jiang
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5974202/
https://ncbi.nlm.nih.gov/pubmed/29876324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2018.00172
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