Combining amplicon sequencing and metabolomics in cirrhotic patients highlights distinctive microbiota features involved in bacterial translocation, systemic inflammation and hepatic encephalopathy

In liver cirrhosis (LC), impaired intestinal functions lead to dysbiosis and possible bacterial translocation (BT). Bacteria or their byproducts within the bloodstream can thus play a role in systemic inflammation and hepatic encephalopathy (HE). We combined 16S sequencing, NMR metabolomics and netw...

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Udgivet i:Sci Rep
Main Authors: Iebba, Valerio, Guerrieri, Francesca, Di Gregorio, Vincenza, Levrero, Massimo, Gagliardi, Antonella, Santangelo, Floriana, Sobolev, Anatoly P., Circi, Simone, Giannelli, Valerio, Mannina, Luisa, Schippa, Serena, Merli, Manuela
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5974022/
https://ncbi.nlm.nih.gov/pubmed/29844325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-26509-y
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