A bioinspired microfluidic model of liquid plug-induced mechanical airway injury

Occlusion of distal airways due to mucus plugs is a key pathological feature common to a wide variety of obstructive pulmonary diseases. Breathing-induced movement of airway mucus plugs along the respiratory tract has been shown to generate abnormally large mechanical stresses, acting as an insult t...

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Bibliographic Details
Published in:Biomicrofluidics
Main Authors: Song, Joseph W., Paek, Jungwook, Park, Kyu-Tae, Seo, Jeongyun, Huh, Dongeun
Format: Artigo
Language:Inglês
Published: AIP Publishing LLC 2018
Subjects:
SPECIAL TOPIC: BIO-TRANSPORT PROCESSES AND DRUG DELIVERY IN PHYSIOLOGICAL MICRO-DEVICES
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5973896/
https://ncbi.nlm.nih.gov/pubmed/29887935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.5027385
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