Inhibition of high shear arterial thrombosis by charged nanoparticles

Platelet accumulation under high shear rates at the site of atherosclerotic plaque rupture leads to myocardial infarction and stroke. Current antiplatelet therapies remain ineffective within a large percentage of the population, while presenting significant risks for bleeding. We explore a novel way...

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Bibliografiske detaljer
Udgivet i:Biomicrofluidics
Main Authors: Griffin, Michael T., Zhu, Yuanzheng, Liu, Zixiang, Aidun, Cyrus K., Ku, David N.
Format: Artigo
Sprog:Inglês
Udgivet: AIP Publishing LLC 2018
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SPECIAL TOPIC: BIO-TRANSPORT PROCESSES AND DRUG DELIVERY IN PHYSIOLOGICAL MICRO-DEVICES
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5973895/
https://ncbi.nlm.nih.gov/pubmed/29887934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.5025349
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