Inhibition of high shear arterial thrombosis by charged nanoparticles

Platelet accumulation under high shear rates at the site of atherosclerotic plaque rupture leads to myocardial infarction and stroke. Current antiplatelet therapies remain ineffective within a large percentage of the population, while presenting significant risks for bleeding. We explore a novel way...

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Publicat a:Biomicrofluidics
Autors principals: Griffin, Michael T., Zhu, Yuanzheng, Liu, Zixiang, Aidun, Cyrus K., Ku, David N.
Format: Artigo
Idioma:Inglês
Publicat: AIP Publishing LLC 2018
Matèries:
SPECIAL TOPIC: BIO-TRANSPORT PROCESSES AND DRUG DELIVERY IN PHYSIOLOGICAL MICRO-DEVICES
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5973895/
https://ncbi.nlm.nih.gov/pubmed/29887934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.5025349
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