Genome-wide significant risk factors on chromosome 19 and the APOE locus

The apolipoprotein E (APOE) gene on chromosome 19q13.32, was the first, and remains the strongest, genetic risk factor for Alzheimer’s disease (AD). Additional signals associated with AD have been located in chromosome 19, including ABCA7 (19p13.3) and CD33 (19q13.41). The ABCA7 gene has been replic...

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Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Moreno-Grau, Sonia, Hernández, Isabel, Heilmann-Heimbach, Stefanie, Ruiz, Susana, Rosende-Roca, Maitée, Mauleón, Ana, Vargas, Liliana, Rodríguez-Gómez, Octavio, Alegret, Montserrat, Espinosa, Ana, Ortega, Gemma, Aguilera, Nuria, Abdelnour, Carla, Neuroimaging Initiative, Alzheimer’s Disease, Gil, Silvia, Maier, Wolfgang, Sotolongo-Grau, Oscar, Tárraga, Lluís, Ramirez, Alfredo, López-Arrrieta, Jesús, Antúnez, Carmen, Serrano-Ríos, Manuel, Boada, Mercè, Ruiz, Agustín
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2018
Sujets:
Research Papers: Gerotarget (Focus on Aging)
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5973862/
https://ncbi.nlm.nih.gov/pubmed/29872490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25083
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