Distinct chromatin functional states correlate with HIV latency reactivation in infected primary CD4(+) T cells

Human immunodeficiency virus (HIV) infection is currently incurable, due to the persistence of latently infected cells. The ‘shock and kill’ approach to a cure proposes to eliminate this reservoir via transcriptional activation of latent proviruses, enabling direct or indirect killing of infected ce...

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Vydáno v:eLife
Hlavní autoři: Battivelli, Emilie, Dahabieh, Matthew S, Abdel-Mohsen, Mohamed, Svensson, J Peter, Tojal Da Silva, Israel, Cohn, Lillian B, Gramatica, Andrea, Deeks, Steven, Greene, Warner C, Pillai, Satish K, Verdin, Eric
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2018
Témata:
Microbiology and Infectious Disease
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5973828/
https://ncbi.nlm.nih.gov/pubmed/29714165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.34655
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