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MTHFR 677C → T genotype modulates the effect of a 5-year supplementation with B-vitamins on homocysteine concentration: The SU.FOL.OM3 randomized controlled trial

AIMS: To study how MTHFR 677C→T genotype modulates the effect of supplementation with B-vitamins on total homocysteine (tHcy) and B-vitamin concentrations. METHODS: 2381 patients with a personal history of cardiovascular disease were randomly assigned to one of four groups: 1) B-vitamins alone (560...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Fezeu, Leopold K., Ducros, Veronique, Guéant, Jean-Louis, Guilland, Jean-Claude, Andreeva, Valentina A., Hercberg, Serge, Galan, Pilar
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5973566/
https://ncbi.nlm.nih.gov/pubmed/29813097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0193352
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