A strategy for L-isoleucine dioxygenase screening and 4-hydroxyisoleucine production by resting cells

L-Isoleucine dioxygenase (IDO) specifically converts L-isoleucine(L-Ile) to 4-hydroxyisoleucine(4-HIL). To obtain IDO with improved activity, a strategy was developed that is dependent on the restoration of succinate-minus E. coli cell growth by the coupling of L-Ile hydroxylation and the oxidation...

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Detalhes bibliográficos
Publicado no:Bioengineered
Main Authors: Zhang, Chenglin, Ma, Jie, Li, Zhixiang, Liang, Yunlong, Xu, Qingyang, Xie, Xixian, Chen, Ning
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5972919/
https://ncbi.nlm.nih.gov/pubmed/28430004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21655979.2017.1304872
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