Human Papillomavirus 16 E7 Stabilizes APOBEC3A Protein by Inhibiting Cullin 2-Dependent Protein Degradation

APOBEC3 (A3) mutation signatures have been observed in a variety of human cancer genomes, including those of cervical and head and neck cancers caused by human papillomavirus (HPV) infection. However, the driving forces that promote off-target A3 activity remain mostly unclear. Here, we report a mec...

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Dettagli Bibliografici
Pubblicato in:J Virol
Autori principali: Westrich, Joseph A., Warren, Cody J., Klausner, Michael J., Guo, Kejun, Liu, Chang-Wei, Santiago, Mario L., Pyeon, Dohun
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2018
Soggetti:
Virus-Cell Interactions
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5972886/
https://ncbi.nlm.nih.gov/pubmed/29367246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01318-17
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