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Hepatitis B Virus Subverts the Autophagy Elongation Complex Atg5-12/16L1 and Does Not Require Atg8/LC3 Lipidation for Viral Maturation

Previous studies indicated that hepatitis B virus (HBV) stimulates autophagy to favor its production. To understand how HBV co-opts autophagy as a proviral machinery, we studied the roles of key autophagy proteins in HBV-replicating liver cell cultures. RNA interference-mediated silencing of Atg5, A...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Döring, Tatjana, Zeyen, Lisa, Bartusch, Christina, Prange, Reinhild
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5972863/
https://ncbi.nlm.nih.gov/pubmed/29367244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01513-17
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