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Germ Line IgM Is Sufficient, but Not Required, for Antibody-Mediated Alphavirus Clearance from the Central Nervous System

Sindbis virus (SINV) infection of neurons in the brain and spinal cord in mice provides a model system for investigating recovery from encephalomyelitis and antibody-mediated clearance of virus from the central nervous system (CNS). To determine the roles of IgM and IgG in recovery, we compared the...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Nilaratanakul, Voraphoj, Chen, Jie, Tran, Oanh, Baxter, Victoria K., Troisi, Elizabeth M., Yeh, Jane X., Griffin, Diane E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5972861/
https://ncbi.nlm.nih.gov/pubmed/29321331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02081-17
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