Prostate cancer chemoprevention by sulforaphane in a preclinical mouse model is associated with inhibition of fatty acid metabolism

Increased de novo synthesis of fatty acids is a rather unique and targetable mechanism of human prostate cancer. We have shown previously that oral administration of sulforaphane (SFN) significantly inhibits the incidence and/or burden of prostatic intraepithelial neoplasia and well-differentiated a...

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Bibliographic Details
Published in:Carcinogenesis
Main Authors: Singh, Krishna B, Kim, Su-Hyeong, Hahm, Eun-Ryeong, Pore, Subrata K, Jacobs, Bruce L, Singh, Shivendra V
Format: Artigo
Language:Inglês
Published: Oxford University Press 2018
Subjects:
Inflammation, Microenvironment and Prevention
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5972626/
https://ncbi.nlm.nih.gov/pubmed/29668854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgy051
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