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Evolution of DNAase I Hypersensitive Sites in MHC Regulatory Regions of Primates

It has been challenging to determine the disease-causing variant(s) for most major histocompatibility complex (MHC)-associated diseases. However, it is becoming increasingly clear that regulatory variation is pervasive and a fundamentally important mechanism governing phenotypic diversity and diseas...

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Vydáno v:Genetics
Hlavní autoři: Jin, Yabin, Gittelman, Rachel M., Lu, Yueer, Liu, Xiaohui, Li, Ming D., Ling, Fei, Akey, Joshua M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Genetics Society of America 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5972428/
https://ncbi.nlm.nih.gov/pubmed/29669733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.118.301028
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