Is the purinergic pathway involved in the pathology of COPD? Decreased lung CD39 expression at initial stages of COPD

BACKGROUND: Extracellular adenosine triphosphate (ATP) is up-regulated in the airways of patients with chronic obstructive pulmonary disease (COPD), resulting in increased inflammation, bronchoconstriction, and cough. Although extracellular ATP levels are tightly controlled by nucleoside triphosphat...

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Detalhes bibliográficos
Publicado no:Respir Res
Main Authors: Aliagas, Elisabet, Muñoz-Esquerre, Mariana, Cuevas, Ester, Careta, Oriol, Huertas, Daniel, López-Sánchez, Marta, Escobar, Ignacio, Dorca, Jordi, Santos, Salud
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5972409/
https://ncbi.nlm.nih.gov/pubmed/29807526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-018-0793-0
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