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Translational readthrough-promoting drugs enhance pseudoknot-mediated suppression of the stop codon at the Moloney murine leukemia virus gag–pol junction

Translational readthrough-promoting drugs enhance the incorporation of amino acids at stop codons and can thus bypass premature termination during protein synthesis. The polymerase (Pol) proteins of Moloney murine leukemia virus (MoMLV) are synthesized as a large Gag–Pol fusion protein, formed by th...

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Pubblicato in:J Gen Virol
Autori principali: Green, Lisa, Goff, Stephen P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Microbiology Society 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5972331/
https://ncbi.nlm.nih.gov/pubmed/26382736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/jgv.0.000284
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