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T Cell Receptor Alpha Chain Genes in the Teleost Ballan Wrasse (Labrus bergylta) Are Subjected to Somatic Hypermutation

Previously, somatic hypermutation (SHM) was considered to be exclusively associated with affinity maturation of antibodies, although it also occurred in T cells under certain conditions. More recently, it has been shown that SHM generates diversity in the variable domain of T cell receptor (TCR) in...

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Bibliografske podrobnosti
izdano v:Front Immunol
Main Authors: Bilal, Sumaira, Lie, Kai Kristoffer, Sæle, Øystein, Hordvik, Ivar
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5972329/
https://ncbi.nlm.nih.gov/pubmed/29872436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01101
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