Ionizing Radiation-Induced Cellular Senescence in Normal, Non-transformed Cells and the Involved DNA Damage Response: A Mini Review

Cellular senescence is identified by a living cell in irreversible and persistent cell cycle arrest in response to various cellular stresses. Senescent cells secrete senescence-associated secretory phenotype factors that can amplify cellular senescence and alter the microenvironments. Radiotherapy,...

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Detalles Bibliográficos
Publicado en:Front Pharmacol
Autores principales: Li, Mengqian, You, Liting, Xue, Jianxin, Lu, You
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5972185/
https://ncbi.nlm.nih.gov/pubmed/29872395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00522
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