A high-fat diet stimulates fibroblast growth factor 23 formation in mice through TNFα upregulation

BACKGROUND/OBJECTIVES: Bone-derived fibroblast growth factor 23 (FGF23) is a hormone that suppresses renal phosphate reabsorption and calcitriol (i.e., 1,25(OH)(2)D(3)) formation together with its co-receptor Klotho. FGF23- or Klotho-deficient mice suffer from rapid aging with multiple age-associate...

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Detalhes bibliográficos
Publicado no:Nutr Diabetes
Main Authors: Glosse, Philipp, Fajol, Abul, Hirche, Frank, Feger, Martina, Voelkl, Jakob, Lang, Florian, Stangl, Gabriele I., Föller, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5972144/
https://ncbi.nlm.nih.gov/pubmed/29807981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41387-018-0037-x
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