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Transforming Growth Factor β Receptor Signaling and Endocytosis Are Linked through a COOH Terminal Activation Motif in the Type I Receptor

Transforming growth factor β (TGF-β) coordinates a number of biological events important in normal and pathophysiological growth. In this study, deletion and substitution mutations were used to identify receptor motifs modulating TGF-β receptor activity. Initial experiments indicated that a COOH-ter...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Principais autores: Garamszegi, Nandor, Doré, Jules J. E., Penheiter, Sumedha G., Edens, Maryanne, Yao, Diying, Leof, Edward B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Cell Biology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC59721/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11553725/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.12.9.2881
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