Evaluation of the Antifungal Activity of the Novel Oral Glucan Synthase Inhibitor SCY-078, Singly and in Combination, for the Treatment of Invasive Aspergillosis

Invasive aspergillosis remains a major cause of death among the immunocompromised population and those receiving long-term immunosuppressive therapy. In light of increased azole resistance, variable outcomes with existing echinocandin monotherapy and combination therapy, and persistent high mortalit...

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Udgivet i:Antimicrob Agents Chemother
Main Authors: Ghannoum, M., Long, L., Larkin, E. L., Isham, N., Sherif, R., Borroto-Esoda, K., Barat, S., Angulo, D.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2018
Fag:
Susceptibility
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5971594/
https://ncbi.nlm.nih.gov/pubmed/29610204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00244-18
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