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Sequential Activities of Phosphoinositide 3-Kinase, PKB/Akt, and Rab7 during Macropinosome Formation in Dictyostelium

Macropinocytosis plays an important role in the internalization of antigens by dendritic cells and is the route of entry for many bacterial pathogens; however, little is known about the molecular mechanisms that regulate the formation or maturation of macropinosomes. Like dendritic cells, Dictyostel...

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Autors principals: Rupper, Adam, Lee, Kyung, Knecht, David, Cardelli, James
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC59715/
https://ncbi.nlm.nih.gov/pubmed/11553719
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