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Small molecules that inhibit the late stage of Munc13-4–dependent secretory granule exocytosis in mast cells
Ca(2+)-dependent secretory granule fusion with the plasma membrane is the final step for the exocytic release of inflammatory mediators, neuropeptides, and peptide hormones. Secretory cells use a similar protein machinery at late steps in the regulated secretory pathway, employing protein isoforms f...
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Publicado no: | J Biol Chem |
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Main Authors: | , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Biochemistry and Molecular Biology
2018
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5971468/ https://ncbi.nlm.nih.gov/pubmed/29615494 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.001547 |
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