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Dicentric Chromosome Stretching during Anaphase Reveals Roles of Sir2/Ku in Chromatin Compaction in Budding Yeast

We have used mitotic spindle forces to examine the role of Sir2 and Ku in chromatin compaction. Escherichia coli lac operator DNA was placed between two centromeres on a conditional dicentric chromosome in budding yeast cells and made visible by expression of a lac repressor–green fluorescent fusion...

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Detalhes bibliográficos
Main Authors: Thrower, Douglas A., Bloom, Kerry
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC59714/
https://ncbi.nlm.nih.gov/pubmed/11553718
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