Screening and Characterizing Tyrosinase Inhibitors from Salvia miltiorrhiza and Carthamus tinctorius by Spectrum-Effect Relationship Analysis and Molecular Docking

Tyrosinase (TYR) is a rate-limiting enzyme in the synthesis of melanin, while direct TYR inhibitors are a class of important clinical antimelanoma drugs. This study established a spectrum-effect relationship analysis method and high-performance liquid chromatography-mass spectrometry (LC-MS) analysi...

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Publicado en:J Anal Methods Chem
Autores principales: Wang, Ya-Li, Hu, Guang, Zhang, Qian, Yang, Yu-Xiu, Li, Qiao-Qiao, Hu, Yuan-Jia, Chen, Hua, Yang, Feng-Qing
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi 2018
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5971358/
https://ncbi.nlm.nih.gov/pubmed/29862119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/2141389
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