CENP-E Is Essential for Reliable Bioriented Spindle Attachment, but Chromosome Alignment Can Be Achieved via Redundant Mechanisms in Mammalian Cells

CENP-E is a kinesin-like protein that when depleted from mammalian kinetochores leads to mitotic arrest with a mixture of aligned and unaligned chromosomes. In the present study, we used immunofluorescence, video, and electron microscopy to demonstrate that depletion of CENP-E from kinetochores via...

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Detalles Bibliográficos

Publicado en:	Mol Biol Cell
Principais autores:	McEwen, Bruce F., Chan, Gordon K.T., Zubrowski, Beata, Savoian, Matthew S., Sauer, Matthew T., Yen, Tim J.
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Cell Biology 2001
Assuntos:	Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC59712/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11553716/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.12.9.2776
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