Regulatory γδ T cells induced by G-CSF participate in acute graft-versus-host disease regulation in G-CSF-mobilized allogeneic peripheral blood stem cell transplantation

BACKGROUND: The immunomodulatory effects of granulocyte colony-stimulating factor (G-CSF) on T cells result in a low incidence of acute graft-versus-host disease (aGVHD) in G-CSF-mobilized allogeneic peripheral blood stem cell transplantation (G-PBSCT). However, the exact mechanism remains unclear....

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Udgivet i:J Transl Med
Main Authors: Xuan, Li, Wu, Xiuli, Qiu, Dan, Gao, Li, Liu, Hui, Fan, Zhiping, Huang, Fen, Jin, Zhenyi, Sun, Jing, Li, Yangqiu, Liu, Qifa
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5970446/
https://ncbi.nlm.nih.gov/pubmed/29801459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-018-1519-2
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