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HMGB1 from hypoxic trophoblasts promotes endothelial microparticle production and thrombophilia in preeclampsia
OBJECTIVE: Thrombophilia is a major complication in preeclampsia (PE), a disease associated with placental hypoxia and trophoblast inflammation. PE women are known to have increased circulating microparticles (MPs) that are pro-coagulant, but the underlying mechanisms remain unclear. In this study,...
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Publicado no: | Arterioscler Thromb Vasc Biol |
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Main Authors: | , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2018
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5970057/ https://ncbi.nlm.nih.gov/pubmed/29650693 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.118.310940 |
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