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HMGB1 from hypoxic trophoblasts promotes endothelial microparticle production and thrombophilia in preeclampsia

OBJECTIVE: Thrombophilia is a major complication in preeclampsia (PE), a disease associated with placental hypoxia and trophoblast inflammation. PE women are known to have increased circulating microparticles (MPs) that are pro-coagulant, but the underlying mechanisms remain unclear. In this study,...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Hu, Yae, Yan, Ruhong, Zhang, Ce, Zhou, Zhichao, Liu, Meng, Wang, Can, Zhang, Hong, Dong, Liang, Zhou, Tiantian, Wu, Yi, Dong, Ningzheng, Wu, Qingyu
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5970057/
https://ncbi.nlm.nih.gov/pubmed/29650693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.118.310940
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