HMGA2 cooperates with either p27(kip1) deficiency or Cdk4(R24C) mutation in pituitary tumorigenesis

We have previously reported a critical role of HMGA proteins in pituitary tumorigenesis since either the Hmga1 or Hmga2 gene overexpression/activation induces the development of mixed growth hormone/prolactin cell pituitary adenomas by activating the E2F transcription factor 1, and then enhancing th...

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Détails bibliographiques
Publié dans:Cell Cycle
Auteurs principaux: Fedele, Monica, Paciello, Orlando, De Biase, Davide, Monaco, Mario, Chiappetta, Gennaro, Vitiello, Michela, Barbieri, Antonio, Rea, Domenica, Luciano, Antonio, Papparella, Serenella, Arra, Claudio, Fusco, Alfredo
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2018
Sujets:
Reports
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5969540/
https://ncbi.nlm.nih.gov/pubmed/29157111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2017.1403682
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