Rationale and protocol of the Study Of diabetic Nephropathy with AtRasentan (SONAR) trial: A clinical trial design novel to diabetic nephropathy

AIMS: Individuals with diabetes and chronic kidney disease (CKD) are at high risk for renal events. Recent trials of novel treatments have been negative, possibly because of variability in response to treatment of the target risk factor. Atrasentan is a selective endothelin A receptor antagonist tha...

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Foilsithe in:Diabetes Obes Metab
Main Authors: Heerspink, Hiddo J. L., Andress, Dennis L., Bakris, George, Brennan, John J., Correa‐Rotter, Ricardo, Dey, Jyotirmoy, Hou, Fan Fan, Kitzman, Dalane W., Kohan, Donald, Makino, Hirofumi, McMurray, John, Perkovic, Vlado, Tobe, Sheldon, Wigderson, Melissa, Parving, Hans‐Henrik, de Zeeuw, Dick
Formáid: Artigo
Teanga:Inglês
Foilsithe: Blackwell Publishing Ltd 2018
Ábhair:
Clinical Trial Design
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5969254/
https://ncbi.nlm.nih.gov/pubmed/29405626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/dom.13245
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