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Neutrophilia, gelatinase release and microvascular leakage induced by human mast cell tryptase in a mouse model: Lack of a role of protease‐activated receptor 2 (PAR2)
BACKGROUND: Tryptase, the most abundant protease of the human mast cell, has been implicated as a key mediator of allergic inflammation that acts through activation of PAR2. OBJECTIVES: To investigate the contribution of PAR2 in the pro‐inflammatory actions mediated by tryptase in a mice model. METH...
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| Publicado en: | Clin Exp Allergy |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
John Wiley and Sons Inc.
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5969079/ https://ncbi.nlm.nih.gov/pubmed/29383785 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cea.13108 |
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