DNA damage checkpoint pathway modulates the regulation of skeletal growth and osteoblastic bone formation by parathyroid hormone-related peptide

We previously demonstrated that parathyroid hormone-related peptide (PTHrP) 1-84 knockin (Pthrp KI) mice, which lacked a PTHrP nuclear localization sequence (NLS) and C-terminus, displayed early senescence, defective osteoblastic bone formation, and skeletal growth retardation. However, the mechanis...

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Bibliografische gegevens
Gepubliceerd in:Int J Biol Sci
Hoofdauteurs: Zhang, Ying, Chen, Guangpei, Gu, Zhen, Sun, Haijian, Karaplis, Andrew, Goltzman, David, Miao, Dengshun
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Ivyspring International Publisher 2018
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Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5968843/
https://ncbi.nlm.nih.gov/pubmed/29805302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.23318
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