CD34(−) Orbital Fibroblasts From Patients With Thyroid-Associated Ophthalmopathy Modulate TNF-α Expression in CD34(+) Fibroblasts and Fibrocytes

PURPOSE: Orbital fibroblasts from patients with Graves' disease (GD-OF) express many different cytokines when treated with bovine thyrotropin (bTSH). The present study aimed to determine why TNF-α cannot be induced by bTSH in GD-OF. METHODS: Fibrocytes and GD-OFs were cultivated from donors who...

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Bibliografiske detaljer
Udgivet i:Invest Ophthalmol Vis Sci
Main Authors: Lu, Yan, Atkins, Stephen J., Fernando, Roshini, Trierweiler, Aaron, Mester, Tünde, Grisolia, Ana Beatriz Diniz, Mou, Pei, Novaes, Priscila, Smith, Terry J.
Format: Artigo
Sprog:Inglês
Udgivet: The Association for Research in Vision and Ophthalmology 2018
Fag:
Immunology and Microbiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5968835/
https://ncbi.nlm.nih.gov/pubmed/29847668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.18-23951
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