Effects of human relaxin-2 (serelaxin) on hypoxic pulmonary vasoconstriction during acute hypoxia in a sheep model

PURPOSE: Hypoxia induces pulmonary vasoconstriction with a subsequent increase of pulmonary artery pressure (PAP), which can result in pulmonary hypertension. Serelaxin has shown an increase of pulmonary hemodynamic parameters after serelaxin injection. We therefore investigated the response of pulm...

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Detalhes bibliográficos
Publicado no:Hypoxia (Auckl)
Main Authors: Schiffner, René, Nistor, Marius, Bischoff, Sabine Juliane, Matziolis, Georg, Schmidt, Martin, Lehmann, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5968803/
https://ncbi.nlm.nih.gov/pubmed/29862306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/HP.S165092
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