Repurposing existing medications as cancer therapy: design and feasibility of a randomized pilot investigating propranolol administration in patients receiving hematopoietic cell transplantation

BACKGROUND: Repurposing existing medications for antineoplastic purposes can provide a safe, cost-effective, and efficacious means to further augment available cancer care. Clinical and preclinical studies suggest a role for the ß-adrenergic antagonist (ß-blocker) propranolol in reducing rates of tu...

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Publicado en:BMC Cancer
Main Authors: Knight, Jennifer M., Kerswill, Stephanie A., Hari, Parameswaran, Cole, Steve W., Logan, Brent R., D’Souza, Anita, Shah, Nirav N., Horowitz, Mary M., Stolley, Melinda R., Sloan, Erica K., Giles, Karen E., Costanzo, Erin S., Hamadani, Mehdi, Chhabra, Saurabh, Dhakal, Binod, Rizzo, J. Douglas
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2018
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5968588/
https://ncbi.nlm.nih.gov/pubmed/29793446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-4509-0
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