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Human osteochondritis dissecans fragment-derived chondrocyte characteristics ex vivo, after monolayer expansion-induced de-differentiation, and after re-differentiation in alginate bead culture

BACKGROUND: Autologous chondrocyte implantation (ACI) is a therapy for articular cartilage and osteochondral lesions that relies on notch- or trochlea-derived primary chondrocytes. An alternative cell source for ACI could be osteochondritis dissecans (OCD) fragment-derived chondrocytes. Assessing th...

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Detalhes bibliográficos
Publicado no:BMC Musculoskelet Disord
Main Authors: Aurich, Matthias, Hofmann, Gunther O., Gras, Florian, Rolauffs, Bernd
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5968539/
https://ncbi.nlm.nih.gov/pubmed/29793458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12891-018-2079-6
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