Phenotypic and Transcriptomic Analysis of Peripheral Blood Plasmacytoid and Conventional Dendritic Cells in Early Drug Naïve Rheumatoid Arthritis

OBJECTIVE: Dendritic cells (DCs) are key orchestrators of immune function. To date, rheumatoid arthritis (RA) researchers have predominantly focused on a potential pathogenic role for CD1c+ DCs. In contrast, CD141+ DCs and plasmacytoid DCs (pDCs) have not been systematically examined, at least in ea...

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發表在:Front Immunol
Main Authors: Cooles, Faye A. H., Anderson, Amy E., Skelton, Andrew, Pratt, Arthur G., Kurowska-Stolarska, Mariola S., McInnes, Iain, Hilkens, Catharien M. U., Isaacs, John D.
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2018
主題:
Immunology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5968398/
https://ncbi.nlm.nih.gov/pubmed/29867920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00755
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