Effects of Antiepileptic Drugs on Spontaneous Recurrent Seizures in a Novel Model of Extended Hippocampal Kindling in Mice

Epilepsy is a common neurological disorder characterized by naturally-occurring spontaneous recurrent seizures and comorbidities. Kindling has long been used to model epileptogenic mechanisms and to assess antiepileptic drugs. In particular, extended kindling can induce spontaneous recurrent seizure...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Song, Hongmei, Tufa, Uilki, Chow, Jonathan, Sivanenthiran, Nila, Cheng, Chloe, Lim, Stellar, Wu, Chiping, Feng, Jiachun, Eubanks, James H., Zhang, Liang
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5968120/
https://ncbi.nlm.nih.gov/pubmed/29867462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00451
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