Interleukin-6/Stat3 signaling has an essential role in the host antimicrobial response to urinary tract infection

The signaling networks regulating antimicrobial activity during urinary tract infection (UTI) are incompletely understood. Interleukin-6 (IL-6) levels increase with UTI severity, but the specific contributions of IL-6 to host immunity against bacterial uropathogens are unknown. To clarify this we te...

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Veröffentlicht in:Kidney Int
Hauptverfasser: Ching, Christina B., Gupta, Sudipti, Li, Birong, Cortado, Hanna, Mayne, Nicholas, Jackson, Ashley R., McHugh, Kirk M., Becknell, Brian
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5967986/
https://ncbi.nlm.nih.gov/pubmed/29475562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.kint.2017.12.006
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