Increased podocyte Sirtuin-1 function attenuates diabetic kidney injury

Podocyte injury and loss contribute to the progression of glomerular diseases, including diabetic kidney disease. We previously found that the glomerular expression of Sirtuin-1 (SIRT1) is reduced in human diabetic glomeruli and that the podocyte-specific loss of SIRT1 aggravated albuminuria and wor...

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Bibliografiska uppgifter
I publikationen:Kidney Int
Huvudupphovsmän: Hong, Quan, Zhang, Lu, Das, Bhaskar, Li, Zhengzhe, Liu, Bohan, Cai, Guangyan, Chen, Xiangmei, Chuang, Peter Y., He, John Cijiang, Lee, Kyung
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2018
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5967974/
https://ncbi.nlm.nih.gov/pubmed/29477240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.kint.2017.12.008
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