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Propofol elicits autophagy via endoplasmic reticulum stress and calcium exchange in C2C12 myoblast cell line

In this study, we investigated the relationship between propofol and autophagy and examined whether this relationship depends on ER stress, production of ROS (reactive oxygen species), and disruption of calcium (Ca(2+)) homeostasis. To this end, we measured C2C12 cell apoptosis in vitro, along with...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Chen, Xi, Li, Long-Yun, Jiang, Jin-Lan, Li, Kai, Su, Zhen-Bo, Zhang, Fu-Qiang, Zhang, Wen-Jing, Zhao, Guo-Qing
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5967754/
https://ncbi.nlm.nih.gov/pubmed/29795639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0197934
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