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Phosphatidylinositol (4,5)-bisphosphate targets DOC2B to the plasma membrane

DOC2B is a high-affinity Ca(2+) sensor that translocates from the cytosol to the plasma membrane (PM) and promotes vesicle priming and fusion. However, the molecular mechanism underlying its translocation and targeting to the PM in living cells is not completely understood. DOC2B interacts in vitro...

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Bibliographic Details
Published in:Traffic
Main Authors: Michaeli, Lirin, Gottfried, Irit, Bykhovskaia, Maria, Ashery, Uri
Format: Artigo
Language:Inglês
Published: 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5967617/
https://ncbi.nlm.nih.gov/pubmed/28941037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/tra.12528
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