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Improving draft genome contiguity with reference-derived in silico mate-pair libraries

BACKGROUND: Contiguous genome assemblies are a highly valued biological resource because of the higher number of completely annotated genes and genomic elements that are usable compared to fragmented draft genomes. Nonetheless, contiguity is difficult to obtain if only low coverage data and/or only...

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Publicat a:Gigascience
Autors principals: Grau, José Horacio, Hackl, Thomas, Koepfli, Klaus-Peter, Hofreiter, Michael
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5967465/
https://ncbi.nlm.nih.gov/pubmed/29688527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gigascience/giy029
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