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Exploiting the Hidden Treasure of Detained Introns

Many mammalian genes contain poorly spliced introns, resulting in nuclear detention of partially spliced transcripts, which may be exploited to modulate gene expression. In this issue of Cancer Cell, Braun et al. report that the arginine methyltransferase PRMT5 is critical for tumor cell proliferati...

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Detalles Bibliográficos
Publicado en:Cancer Cell
Autor Principal: Fu, Xiang-Dong
Formato: Artigo
Idioma:Inglês
Publicado: 2017
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5967397/
https://ncbi.nlm.nih.gov/pubmed/29017049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2017.09.005
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