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Genetic Variation of the SusC/SusD Homologs from a Polysaccharide Utilization Locus Underlies Divergent Fructan Specificities and Functional Adaptation in Bacteroides thetaiotaomicron Strains

Genomic differences between gut-resident bacterial strains likely underlie significant interindividual variation in microbiome function. Traditional methods of determining community composition, such as 16S rRNA gene amplicon sequencing, fail to capture this functional diversity. Metagenomic approac...

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Detalhes bibliográficos
Publicado no:mSphere
Main Authors: Joglekar, Payal, Sonnenburg, Erica D., Higginbottom, Steven K., Earle, Kristen A., Morland, Carl, Shapiro-Ward, Sarah, Bolam, David N., Sonnenburg, Justin L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5967196/
https://ncbi.nlm.nih.gov/pubmed/29794055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphereDirect.00185-18
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